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Viloxazine
Viloxazine
Synonyms ICI-58834
Brand names Vicilan, Vivalan, Vivarint
IUPAC name

IUPAC name
2-[(2-ethoxyphenoxy)methyl]morpholine
ChemSpider

5464

DrugBank

None

PubChem

5666

PDB fields

N/A

Formula

C13H19NO3

InChI
InChI
1S/C13H19NO3/c1-2-15-12-5-3-4-6-13(12)17-10-11-9-14-7-8-16-11/h3-6,11,14H,2,7-10H2,1H3</span>
InChIKey
InChIKey
YWPHCCPCQOJSGZ-UHFFFAOYSA-N
SMILES
SMILES
CCOC1=CC=CC=C1OCC2CNCCO2
(Jmol 3D structure)
Mol. mass

237.2949 g/mol

Viloxazine is a selective noradrenaline reuptake inhibitor, with a bicyclic chemistry; it possesses minimal affinity for the mAChRs, H1 and the α adrenergic receptors.[1] It is no longer marketed in any country; it used to be marketed in Europe (including the U.K.).[2] It is taken three times a day due its elimination half-life of 2-5 hours.[1]

External linksEdit

Reference listEdit

  1. 1.0 1.1 Pinder, RM; Brogden, RN; Speight, TM; Avery, GS (June 1977). "Viloxazine: a review of its pharmacological properties and therapeutic efficacy in depressive illness.". Drugs 13 (6): 401–21. PMID 324751. doi:10.2165/00003495-197713060-00001. 
  2. Brayfield, A, ed. (23 September 2011). "Viloxazine Hydrochloride". Martindale: The Complete Drug Reference. London, UK: Pharmaceutical Press. Retrieved 9 August 2014. 


  1. Multi-modal_antidepressants

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