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Tyramine
Tyramine
Synonyms 4-hydroxyphenethylamine, systogene, tocosine, tyrosamine, uteramine
Brand names Mydrial-Atropin
IUPAC name

IUPAC name
4-(2-aminoethyl)phenol
ChemSpider

5408

DrugBank

None

PubChem

5610

PDB fields

N/A

Formula

C8H11NO

InChI
InChI
1S/C8H11NO/c9-6-5-7-1-3-8(10)4-2-7/h1-4,10H,5-6,9H2
InChIKey
InChIKey
DZGWFCGJZKJUFP-UHFFFAOYSA-N
SMILES
SMILES
C1=CC(=CC=C1CCN)O
(Jmol 3D structure)
Mol. mass

137.1790 g/mol

Tyramine is an trace amine neurotransmitter, that is a potent TAAR1 agonist, hence inducing monoamine release.[1] Exogenous sources (like dietary sources) have little pressor effects (blood pressure-elevating effects; via inducing catecholamine release) in healthy individuals, but those treated with monoamine oxidase inhibitors (especially irreversible inhibitors) can experience a hypertensive crises due to this pressor effects.

External linksEdit

Reference listEdit

  1. Zucchi, R; Chiellini, G; Scanlan, TS; Grandy, DK (December 2006). "Trace amine-associated receptors and their ligands.". British Journal of Pharmacology 149 (8): 967–78. PMC 2014643. PMID 17088868. doi:10.1038/sj.bjp.0706948. 

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