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Tumour necrosis factor alpha
TNFA ST
3D structure of TNF-alpha, based on PDB 1TNF.
300px 1TNF
Animated 3D structure of TNF-alpha, based on PDB 1TNF.

Synonyms

Cachectin, TNF-α, TNF-alpha, tumor necrosis factor alpha,

PDB

Search for UniProt ID P01375.

Example IDs
1TNF (RCSB, PDBe; X-ray), 2AZ5 (RCSB, PDBe; X-ray)

Proteopedia

Tumour necrosis factor alpha

Jmol applet of 1TNF

1TNF.

No. of amino acids

157

FASTA

Sequence
VRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL

MeSH

D014409
Review search.

UniProt

P01375

Entrez

7124

Tumour necrosis factor alpha (TNF-α) is a pro-inflammatory cytokine that is produced predominantly by macrophages and can induce death in various cancer cell lines.

External linksEdit

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