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Thalidomide
Thalidomide

2D structure of the racemate
(R)-thalidomide

(R)-thalidomide
(S)-thalidomide2

(S)-thalidomide

Synonyms

E-217, K-17, NSC-66847, Sedoval

Brand names

Talidex, Thaled, Thalomid

IUPAC name

IUPAC
(3RS)-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione

ChemSpider

5233

DrugBank

DB01041

PubChem

5426

CIF fields

CODID 1513335

InChI

InChI
1S/C13H10N2O4/c16-10-6-5-9(11(17)14-10)15-12(18)7-3-1-2-4-8(7)13(15)19/h1-4,9H,5-6H2,(H,14,16,17)

InChIKey

InChIKey
UEJJHQNACJXSKW-UHFFFAOYSA-N

SMILES

SMILES
O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC=CC=C12
(Jmol 3D structure)

Formula

C13H10N2O4

Mol. mass

258.2295


Thalidomide is an immunomodulatory drug (IMiDs) that is well-known for the terrible birth defects it caused in the 1950s and 1960s when it was being used as a sleep aid and treatment for morning sickness in pregnant women. It is primarily used to treat multiple myeloma and erythema nodosum leprosum.[1]


External linksEdit

Reference listEdit

  1. Brayfield, A, ed. (15 January 2014). "Thalidomide". Martindale: The Complete Drug Reference. London, UK: Pharmaceutical Press. Retrieved 27 November 2014. 

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