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Sjögren syndrome
Sjögren syndrome
A histopathologic image of lymphoid infiltration of the minor salivary gland.
Synonyms
Synonyms
SS, Sicca syndrome (see below),
MeSH D012859
ICD-9

710.2

ICD-10

M35.0

eMedicine

Overview
Presentation
DDx
Workup
Treatment
Medication}

MedlinePlus

000456

Patient.co.uk

Professional Reference
Patient Reference

OMIM

270150

BHC

Sjögren syndrome

Wikipedia

Sjögren syndrome

Sjögren syndrome is a chronic autoimmune disease that primarily affects the salivary and lacrimal (tear) glands, but it can affect other organs (which are affected in approximately a third of all cases) too, including: kidneys, joints, lungs, nerves, etc.[1] It most commonly occurs between the ages of 50-60 years and like many other autoimmune diseases (e.g., Systemic lupus erythematosus) shows a clear female preponderance (on average they are about nine times more likely to develop the disorder than their male counterparts).[1] It is the second most common autoimmune disease in the Western world, after systemic lupus erythematosus.[2] 

When symptoms are limited to the salivary and lacrimal glands the disorder is called Sicca syndrome.[2] These symptoms include: parotid gland (the largest salivary gland) swelling, dry eyes and mouth.[2]



External linksEdit

Reference listEdit

  1. 1.0 1.1 Kumar, V; Abbas, AK; Aster, AC (July 2014). "Chapter 6. Diseases of the Immune System". Robbins & Cotran Pathologic Basis of Disease 9e. Philadelphia, USA: Saunders. ISBN 978-0-8089-2450-0. 
  2. 2.0 2.1 2.2 Miller, AV; Ranatunga, SK; Tumyan, A; Francis, ML; Pema, K (9 July 2014). Diamond, HS; Barrett, TL; Butler, DF; Dire, DJ; Elston, DM; Farina, GA; Goldberg, E; Kulkarni, R; Lozada, CJ; Miller, JJ; Narbutt, J; Phelan, D; Ranatunga, SKM; Schwartz, RA; Sysa-Jedrzejowska, A; Talavera, F; Torzecka, JD; Zalewska, A, ed. "Sjogren Syndrome". Medscape Reference. New York, USA: WebMD. Retrieved 21 December 2014. 

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