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Serotonin
Serotonin
Synonyms 5-hydroxytryptamine, 5-HT, enteramine
Brand names Not marketed
IUPAC name

IUPAC name
3-(2-aminoethyl)-1H-indol-5-ol
ChemSpider

5013

DrugBank

None

PubChem

5202

PDB fields

N/A

Formula

C10H12N2O

InChI
InChI
1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2
InChIKey
InChIKey
QZAYGJVTTNCVMB-UHFFFAOYSA-N
SMILES
SMILES
C1=CC2=C(C=C1O)C(=CN2)CCN
(Jmol 3D structure)
Mol. mass

176.2151 g/mol

Serotonin is a monoamine neurotransmitter, with other roles in the body, which is biosynthesized from the amino acid L-tryptophan with an intermediary step in its synthesis being 5-hydroxytryptophan (5-HTP; also called by the INN oxitriptan). Its roles are diverse and include: in sleep, memory, learning, perception, mood, addiction, blood clotting, stomach acid secretion, temperature regulation, digestive tract motility (how food moves through the digestive tract) and appetite. It also serves as a precursor to melatonin. It produces it effects by acting at the 5-HT1 (subtypes A, B, D, E, F), 5-HT2 (subtypes A, B, C), 5-HT3, 5-HT4, 5-HT5A, 5-HT6 and 5-HT7 receptors.

Precursors to serotonin


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