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Sarcoidosis
Sarcoidosis chest X-ray
Chest X-ray of someone with sarcoidosis
Synonyms
Synonyms
Besnier-Boeck Disease, Besnier-Boeck-Schaumann Syndrome, Boeck('s) disease/syndrome, etc.
MeSH D012507
ICD-9

135

ICD-10

D86

eMedicine

Overview
Presentation
DDx
Workup
Treatment
Medication}

MedlinePlus

000076

Patient.co.uk

Professional Reference
Patient Reference

OMIM

181000

BHC

Sarcoidosis

Wikipedia

Sarcoidosis

Sarcoidosis is a systemic inflammatory condition of unknown aetiology that causes the formation of granulomas, most commonly in the lungs or lymph nodes, although any organ can be affected.[1] While the disease can, albeit rarely, be life-threatening it often resolves without any medical intervention and in about 5-60% of cases it can even cause no symptoms and rather be discovered by accident during routine chest imaging.[1][2] Its most common manifestations include:[1][3]

  • Lymphadenopathy, especially of the hilar lymph nodes in the chest cavity
  • Lung involvement (~50% of cases), from granuloma formation to pulmonary fibrosis
  • Systemic complaints (occurring in about 45% of cases) like fever, fatigue, night sweats and loss of appetite 
  • Ocular manifestations (10-30%) such as uveitis and conjunctivitis.
  • Neurologic manifestations (5-10% of cases), which usually affects the cranial nerves (e.g., facial nerve palsy leading to an asymmetric facial expression), but can affect other peripheral nerves and the brain.
  • Dermatologic manifestations like erythema nodosum and lupus pernio.



External linksEdit

Reference listEdit

  1. 1.0 1.1 1.2 Kamangar, N; Rohani, P; Shorr, AF (31 October 2014). Peters, SP; Talavera, F; Rice, TD; Mosenifar, Z, ed. "Sarcoidosis". Medscape Reference. New York, USA: WebMD. Retrieved 5 December 2014. 
  2. Nunes, H; Bouvry, D; Soler, P; Valeyre, D (19 November 2007). "Sarcoidosis.". Orphanet Journal of Rare Diseases 2: 46. PMC 2169207. PMID 18021432. doi:10.1186/1750-1172-2-46. 
  3. Valeyre, D; Prasse, A; Nunes, H; Uzunhan, Y; Brillet, PY; Müller-Quernheim, J (29 March 2014). "Sarcoidosis.". Lancet 383 (9923): 1155–67. PMID 24090799. doi:10.1016/S0140-6736(13)60680-7. 

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