The Philadelphia chromosome is a chromosomal abnormality seen in a variety of haematologic malignancies, most commonly chronic myeloid leukaemia, but also 20-30% of adult cases of acute lymphoblastic leukaemia (ALL) and 5% of paediatric cases of ALL. It occurs when segments of chromosome 9 gets translocated into chromosome 22.
- MeSH ID D010677
- NCBI Bookshelf provides free book resources on this topic.
- PubMed provides review articles from the past five years (limit to free review articles or to systematic reviews)
- The TRIP database provides clinical publications about evidence-based medicine.
- ↑ Ravandi, F; Kebriaei, P (October 2009). "Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia". Hematology/Oncology Clinics of North America 23 (5): 1043–1063. ISSN 0889-8588. PMC 4091825. PMID 19825452. doi:10.1016/j.hoc.2009.07.007.
- ↑ Kilbourne, J; Case, JT; Cho, DS; Hui, C; Jarnot, M; Koroma, B; Pash, J; Powell, T; Schulman, JL; Sorden, N (2015). "Philadelphia Chromosome". Medical Subject Headings. Bethesda, USA: U.S. National Library of Medicine. Retrieved 13 January 2014.