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Perospirone
Perospirone
Synonyms SM-9018
Brand names Kang Er Ting, Lullan
IUPAC name

IUPAC name
(3aR,7aS)-2-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-3a,4,5,6,7,7a-hexahydroisoindole-1,3-dione
ChemSpider

103202

DrugBank

None

PubChem

115368

PDB fields

N/A

Formula

C23H30N4O2S

InChI
InChI
1S/C23H30N4O2S/c28-22-17-7-1-2-8-18(17)23(29)27(22)12-6-5-11-25-13-15-26(16-14-25)21-19-9-3-4-10-20(19)30-24-21/h3-4,9-10,17-18H,1-2,5-8,11-16H2/t17-,18+
InChIKey
InChIKey
FBVFZWUMDDXLLG-HDICACEKSA-N
SMILES
SMILES
C1CC[C@H]2[C@@H](C1)C(=O)N(C2=O)CCCCN3CCN(CC3)C4=NSC5=CC=CC=C54
(Jmol 3D structure)
Mol. mass

426.5749 g/mol

Perospirone is an atypical antipsychotic (APD) used to treat schizophrenia with a unusually high incidence of movement disorder side effects for an APD.[1][2] It is also significantly less effective than other APDs.[2] It is solely marketed in China and Japan.[1]

External linksEdit

Reference listEdit

  1. 1.0 1.1 Brayfield, A, ed. (23 September 2011). "Perospirone Hydrochloride". Martindale: The Complete Drug Reference. London, UK: Pharmaceutical Press. Retrieved 21 August 2014. 
  2. 2.0 2.1 Kishi, T; Iwata, N (September 2013). "Efficacy and tolerability of perospirone in schizophrenia: a systematic review and meta-analysis of randomized controlled trials.". CNS Drugs 27 (9): 731–41. PMID 23812802. doi:10.1007/s40263-013-0085-7. 

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