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Parkinson disease
Synonyms
Synonyms
Paralysis agitans, Parkinson's disease, Primary Parkinsonism
MeSH D010300
ICD-9

332

ICD-10

G20, F02.3

eMedicine

Overview
Presentation
DDx
Workup
Treatment
Medication}

MedlinePlus

000755

Patient.co.uk

Professional Reference
Patient Reference

OMIM

OMIM
168600
556500
BHC

Parkinson disease

Wikipedia

Parkinson disease

Parkinson disease is a rare neurodegenerative disorder (ND) that leads to the gradual destruction of the dopamine-signalling (“dopaminergic”) neurons of the substantia nigra, which is required for voluntary muscle control. Treatment can significantly improve life expectancy, quality of life, etc. but is purely symptomatic (that is, it deals with the symptoms and does not treat the underlying disease process). Treatment usually consists of dopaminergic drugs such as levodopa, monoamine oxidase B inhibitors, dopamine agonists, etc., but is not, by any means, curative. Death usually occurs from complications of immobility (i.e., the inability to move) like pneumonia or pulmonary embolism (blood clot to the lung, usually the result of a deep vein thrombosis). It is the second most common ND after Alzheimer's disease.

External linksEdit

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