Nicotinic acetylcholine receptors are ligand-gated ion channels that respond to the endogenous ligand, acetylcholine, as well as the exogenous ligand nicotine. They are found primarily in the nervous system where they are crucial to skeletal muscle control, along with cognitive functions such as memory and learning, the release of various other neurotransmitters including dopamine in various parts of the brain, including the mesolimbic pathway.[1][2]

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Reference listEdit

  1. Unwin, N (November 2013). "Nicotinic acetylcholine receptor and the structural basis of neuromuscular transmission: insights from Torpedo postsynaptic membranes.". Quarterly Reviews of Biophysics 46 (4): 283–322. PMC 3820380. PMID 24050525. doi:10.1017/S0033583513000061. 
  2. Papke, RL (1 May 2014). "Merging old and new perspectives on nicotinic acetylcholine receptors.". Biochemical Pharmacology 89 (1): 1–11. PMID 24486571. doi:10.1016/j.bcp.2014.01.029. 

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