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Nefazodone
Nefazodone
Synonyms BMY-13754, MJ-13754-1
Brand names Deprefax, Dutonin, Serzone and many others
IUPAC name

IUPAC name
1-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-3-ethyl-4-(2-phenoxyethyl)-4,5-dihydro-1H-1,2,4-triazol-5-one
ChemSpider

4294

DrugBank

DB00234

PubChem

4449

PDB fields

N/A

Formula

C25H32ClN5O2

InChI
InChI
1S/C25H32ClN5O2/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22/h3-6,8-11,20H,2,7,12-19H2,1H3
InChIKey
InChIKey
VRBKIVRKKCLPHA-UHFFFAOYSA-N
SMILES
SMILES
CCC1=NN(CCCN2CCN(CC2)C2=CC(Cl)=CC=C2)C(=O)N1CCOC1=CC=CC=C1
(Jmol 3D structure)
Mol. mass

264.365 g/mol

Nefazodone is a serotonin antagonist and reuptake inhibitor (SARI) that has been withdrawn from the market in many developed countries (including Australia, Canada, Germany, Italy, New Zealand, Spain, the U.K., etc.), although it is still marketed in Greece and the U.S.A. On top of its SARI activity it also serves as a noradrenaline reuptake inhibitor.



External linksEdit

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