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Multiple sclerosis
MS demyelination CD68
Demyelination typical of MS
Synonyms
Synonyms
Disseminated sclerosis, MS
MeSH D009103
ICD-9

340

ICD-10

G35

eMedicine

Overview
Presentation
DDx
Workup
Treatment
Medication}

MedlinePlus

000737

Patient.co.uk

Professional Reference
Patient Reference

OMIM

126200

BHC

Multiple sclerosis

Wikipedia

Multiple sclerosis

Multiple sclerosis is a CD4+ T cell -mediated autoimmune disease that solely affects the central nervous system; the self-antigen it is directed against is myelin. Its symptoms are wide and diverse but may include: paralysis, incoordination, spasticity, vision problems, muscle weakness, cognitive impairment, fatigue, depression, etc.[1] It cuts life expectancy, on average, by 5-10 years and is treated with immunomodulators and related drugs.[2]


External linksEdit

Reference listEdit

  1. Keegan, BM; Childers, MK; Hooker, EA II; Huff, JS; Lazoff, M; Lorenzo, CT; Nowack, WJ; Salcido, R; Scott, DD; Shi, FD; Talavera, F; Thomas, FP; Vollmer, T; Williamson, SF, ed. (24 November 2014). "Multiple Sclerosis". Medscape Reference. New York, USA: WebMD. 
  2. Compston, A; Coles, A (25 October 2008). "Multiple sclerosis.". Lancet 372 (9648): 1502–17. PMID 18970977. doi:10.1016/S0140-6736(08)61620-7. 

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