Histiologic signs of plasmacytoma
Multiple myeloma is a plasma cell cancer that is considered incurable and hence terminal. Its major symptoms include: bone pain and fractures without an apparent cause, weakness, malaise, bleeding, anaemia, infection, kidney failure, peripheral neuropathies, hypercalcaemia and spinal cord compression. Current therapies (which includes bortezomib, dexamethasone, lenalidomide, melphalan and thalidomide), however, allow the 5-year survival rate to be 35% and the median survival to be 3 years. It is also known to cause type AH and AL amyloidosis.
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- PubMed provides review articles from the past five years (limit to free review articles or to systematic reviews)
- The TRIP database provides clinical publications about evidence-based medicine.