Monogenic diabetes mellitus (MDM), are a family of subtypes of diabetes mellitus that are caused by individual faulty genes (that is, one faulty gene for each individual subtype), there are thirty-two known subtypes, caused by 32 different problem genes.[1] They are usually inherited in an autosomal dominant fashion.[1] There are three major varieties: maturity-onset diabetes of the young (MODY), neonatal diabetes mellitus (NDM) and adult-onset monogenic diabetes mellitus (AOMDM).[1]

MODY is the most common subtype of MDM and usually presents before the age of 25 years, whereas NDM presents before the age of 6 months.[1]

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Reference listEdit

  1. 1.0 1.1 1.2 1.3 Schwitzgebel, VM (March 2014). "Many faces of monogenic diabetes.". Journal of Diabetes Investigation 5 (2): 121–33. PMC 4023572. PMID 24843749. doi:10.1111/jdi.12197. 

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