|Synonyms||Dimethylbiguanide, dimethyldiguanide, Flumamine, N,N-dimethylbiguanide.|
|Brand names||Diabex, Diaformin, Diagemet, Formet, Glucophage, Glucomet, Glumetza, Metabet, Metsol, etc.|
Metformin is an oral antihyperglycaemic that is used in the treatment of type 2 diabetes mellitus, although it has been tried with some modest success in the treatment of type 1 diabetes mellitus. It works by reducing gluconeogenesis in the liver, improving insulin sensitivity and reducing intestinal absorption of sugars. During hyperglycaemia it might also increase the absorption of glucose by cells, hence reducing blood glucose levels.
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- PubMed provides review articles from the past five years (limit to free review articles or to systematic reviews)
- The TRIP database provides clinical publications about evidence-based medicine.