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Lymphadenopathy
Lymphadenopathy
Lymphadenopathy due to infectious mononucleosis.
Synonyms
Synonyms
MeSH D008206
ICD-10

289.1, 289.2, 289.3, 683, 785.6

ICD-10

I88, L04, R59.1

Medscape Reference

Overview
Presentation
DDx
Workup
Treatment
Medication

MedlinePlus

001301

Lymphadenopathy is a symptom that is defined as an enlarged lymph node(s). Its causes are wide and varied, but include (although it is worth noting that this is not a comprehensive list):[1]

  • Amyloidosis
  • Autoimmune diseases/inflammatory diseases, e.g., autoimmune lymphoproliferative syndrome, dermatomyosis, graft-versus-host disease (GVHD), Kawasaki's disease, rheumatoid arthritis (including its juvenile variant), sarcoidosis, Sjögren's syndrome and systemic lupus erythematosus
  • Cancers and lymphoproliferative disorders such as metastatic solid tumours, lymphomas (both Hodgkin's and non-Hodgkin's), Castleman's disease, lymphocytic leukaemia (including acute, chronic and hairy cell) and malignant histiocytosis.
  • Familial Mediterranean Fever
  • Histiocytosis X
  • Hyperthyroidism
  • Hypertriglyceridaemia (severe)
  • Infectious diseases, including bacterial (brucellosis, cat-scratch disease, diphtheria, glanders, leprosy, melioidosis, plague, Q-fever, syphilis, tuberculosis and tularaemia), fungal (e.g., histioplasmosis), parasitic (e.g., leishmaniasis, toxoplasmosis, trypanosomiasis), viral (e.g., with herpesviruses such as herpes simplex, Epstein-Barr virus/cytomegaloviruses [leading to infectious mononucleosis], chickenpox, roseola, Kaposi's sarcoma-associated herpesvirus [KSHV], hepatitis A, B, C, D and E, adenovirus, HIV, measles, rubella, etc.).
  • Lipid storage diseases like Fabry's

NotesEdit


Reference listEdit

  1. Longo, DL; Fauci, AS; Kasper, DL; Hauser, SL; Jameson, JL; Loscalzo, J, ed. (2012). "Chapter 59. Enlargement of Lymph Nodes and Spleen". Harrison's Principles of Internal Medicine, 18e. New York, USA: McGraw-Hill. ISBN 978-0-07174889-6. 

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