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Interleukin-5
300px 1HULw

Synonyms

B-cell differentiation factor I, eosinophil differentiation factor, t-cell replacing factor (TRF)

PDB

Search for UniProt ID P05113.

Example IDs
1HUL (X-ray crystallography)[1]

Proteopedia

N/A

Jmol applet of 1HUL

[1]

No. of amino acids

115

FASTA

Sequence
IPTEIPTSALVKETLALLSTHRTLLIANETLRIPVPVHKNHQLCTEEIFQGIGTLESQTVQGGTVERLFKNLSLIKKYIDGQKKKCGEERRRVNQFLDYLQEFLGVMNTEWIIES

MeSH

D015848

UniProt

P05113

Entrez

3567

Interleukin-5 is produced by helper T cells, mast cells and other granulocytes and it promotes the differentiation and activation of eosinophils, also triggers antigen-induced differentiation of B-cells into plasma cells.[2][3][4][5]


External linksEdit

Reference listEdit

  1. Milburn, MV; Hassell, AM; Lambert, MH; Jordan, SR; Proudfoot, AE; Graber, P; Wells, TN (13 May 1993). "A novel dimer configuration revealed by the crystal structure at 2.4 A resolution of human interleukin-5.". Nature 363 (6425): 172–6. PMID 8483502. doi:10.1038/363172a0. 
  2. Marieb, EN; Hoehn, K (2013). "Chapter 21 The Immune System: Innate and Adaptive Body Defenses". Human Anatomy & Physiology (9th ed.). Boston, USA: Pearson. p. 790. ISBN 978-0-321-74326-8. 
  3. Takatsu, K (2011). "Interleukin-5 and IL-5 receptor in health and diseases.". Proceedings of the Japan Academy. Series B, Physical and Biological Sciences 87 (8): 463–85. PMC 3313690. PMID 21986312. doi:10.2183/pjab.87.463. 
  4. "Interleukin-5". Medical Subject Headings. Bethesda, USA: U.S. National Library of Medicine. 2011. Retrieved 29 October 2014. 
  5. Ishino, T; Robertson, N; Chaiken, I (2005). "Cytokine recognition by human interleukin 5 receptor.". Vitamins and Hormones 71: 321–44. PMID 16112273. doi:10.1016/S0083-6729(05)71011-6. 

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