Table 1: Medical uses of IFN-alfa
Genital warts Limited evidence of efficacy.
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Usually treatment involves
therapy and a
on data from 150 patients found to find any significant therapeutic advantage over treatment with placebo, although there was clear signs of an increased frequency of side effects (including systemic side effects).
As an adjunct to
(5-FU) it seems to provide an efficacy advantage over 5-FU alone.
HSV infections Evidence of speeding up healing when combined with antivirals (e.g., aciclovir); no evidence of improved treatment outcomes.
Kwok, CS; Gibbs, S; Bennett, C; Holland, R; Abbott, R (12 September 2012). "Topical treatments for cutaneous warts.". The Cochrane Database of Systematic Reviews 9: CD001781. PMID 22972052. doi: 10.1002/14651858.CD001781.pub3.
Batista, CS; Atallah, AN; Saconato, H; da Silva, EM (14 April 2010). "5-FU for genital warts in non-immunocompromised individuals.". The Cochrane Database of Systematic Reviews (4): CD006562. PMID 20393949. doi: 10.1002/14651858.CD006562.pub2.
Wilhelmus, KR (8 December 2010). "Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis.". The Cochrane Database of Systematic Reviews (12): CD002898. PMID 21154352. doi: 10.1002/14651858.CD002898.pub4. ↑
Brayfield, A, ed. (19 May 2014). "Interferon Alfa". Martindale: The Complete Drug Reference. London, UK: Pharmaceutical Press . Retrieved . 31 December 2014
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