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Insulin


Synonyms

None notable

PDB

Search for UniProt ID P01308.

Example IDs

Proteopedia

N/A

Jmol applet of 4F8F

4F8F.

No. of amino acids

110

FASTA

Sequence
MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN

MeSH


UniProt

P01308

Entrez

[1]

Insulin is a peptide hormone produced by the β islet cells of the pancreas.[1] It interacts with its own receptor, the insulin receptor, which produces a number of different physiologic responses. For one, it enables cells, especially muscle and adipose (fat) cells, to take in glucose from the bloodstream and utilize it for energy production via glycolysis. Secondly it also reduces gluconeogenesis in the liver and ketone body synthesis for energy production.[1] Thirdly, it increases glycogen production from glucose.[1] Insulin is utilized by the body, along with glucagon, to maintain blood glucose levels: soon after a meal insulin is secreted in response to the rise in blood glucose levels after a meal.[2]:618-620

External linksEdit

Reference listEdit

  1. 1.0 1.1 1.2 Brayfield, A, ed. (8 May 2014). "Insulin". Martindale: The Complete Drug Reference. London, UK: Pharmaceutical Press. Retrieved 28 September 2014. 
  2. Marieb, EN; Hoehn, K (2013). Human Anatomy & Physiology (9th ed. ed.). Boston, USA: Pearson. ISBN 978-0-321-74326-8. 

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