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Immunoglobulin M (IgM) are antibodies that are the first antibodies produced during an immune response, prior to class switching to other antibody isotypes. They are the largest antibody molecules as they are generally pentamers, although a monomer variant exists as a cell surface receptor for B-cells. Along with IgG it is one of the major antibody isotypes that is responsible for activating complement.[1]

Reference listEdit

  1. Kumar, V; Abbas, AK; Aster, AC (July 2014). "Chapter 6. Diseases of the Immune System". Robbins & Cotran Pathologic Basis of Disease 9e. Philadelphia, USA: Saunders. p. 198. ISBN 978-0-8089-2450-0. 

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