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Goodpasture syndrome
Synonyms
Synonyms
Anti-GBM disease,[note 1] GPS
MeSH D019867
ICD-9

446.21

ICD-10

M31.0

eMedicine

Overview
Presentation
DDx
Workup
Treatment
Medication}

MedlinePlus

000142

Patient.co.uk

Professional Reference

OMIM

D019867

Wikipedia

Goodpasture syndrome

Goodpasture syndrome is a rare autoimmune disease that is generally considered a predominantly antibody-mediated (or type IIhypersensitivity for which the causal autoantibody is believed to be one directed against the α3 chain of collagen IV which is found predominantly in the membrane basements of the glomeruli[note 2] and alveoli of the kidneys and lungs, respectively.[1]



External linksEdit

NotesEdit

  1. If it is limited to the kidneys only.
  2. Hence the reason for the most common name of this autoantibody, anti-glomerular membrane basement (GBM) antibody.

Reference listEdit

  1. Kathuria, P; Sanghera, P; Stevenson, FT; Sharma, S (12 December 2014). Batuman, V; Lederer, E; Lohr, JW; Talavera, F; Verrelli, M, ed. "Goodpasture Syndrome". Medscape Reference. New York, USA: WebMD. Retrieved 9 January 2015. 

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