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Fluvoxamine
Fluvoxamine
Synonyms None notable
Brand names Faverin, Luvox, Movox, Voxam and others
IUPAC name

IUPAC name
(2-aminoethoxy)({5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene})amine
ChemSpider

3287

DrugBank

DB00176

PubChem

5324346

PDB fields

N/A

Formula

C15H21F3N2O2

InChI
InChI
1S/C15H21F3N2O2/c1-21-10-3-2-4-14(20-22-11-9-19)12-5-7-13(8-6-12)15(16,17)18/h5-8H,2-4,9-11,19H2,1H3/b20-14+
InChIKey
InChIKey
CJOFXWAVKWHTFT-XSFVSMFZSA-N
SMILES
SMILES
COCCCCC(=NOCCN)C1=CC=C(C=C1)C(F)(F)F
(Jmol 3D structure)
Mol. mass

318.33465 g/mol

Fluvoxamine is a selective serotonin reuptake inhibitor (SSRI) that is used primarily to treat obsessive-compulsive disorder, although in some countries it is also approved to treat depression. It also potently inhibits CYP1A2 and CYP2C19, moderately inhibits CYP2C9, CYP2D6 and CYP3A4.[1][2] It is the only achiral clinically-used second-generation monoamine reuptake inhibitor (which is a generalized class including SSRIs, SNRIs, NRI, NDRI, etc.).

3D structuresEdit

3D structures
Fluvoxamine3D
250px Fluvoxamine


External linksEdit

Reference listEdit

  1. Brunton, L; Chabner, B; Knollman, B (2010). Goodman and Gilman's The Pharmacological Basis of Therapeutics (12th ed.). New York, USA: McGraw-Hill Professional. ISBN 978-0-07-162442-8. 
  2. Hemeryck, A; Belpaire, FM (February 2002). "Selective serotonin reuptake inhibitors and cytochrome P-450 mediated drug-drug interactions: an update.". Current Drug Metabolism 3 (1): 13–37. PMID 11876575. doi:10.2174/1389200023338017. 

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