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Structure of methotrexate based on PDB 3EIG. Based on:

Volpato, JP; Yachnin, BJ; Blanchet, J; Guerrero, V; Poulin, L; Fossati, E; Berghuis, AM; Pelletier, JN (24 July 2009). "Multiple conformers in active site of human dihydrofolate reductase F31R/Q35E double mutant suggest structural basis for methotrexate resistance.". The Journal of Biological Chemistry 284 (30): 20079–89. PMC 2740434. PMID 19478082. doi:10.1074/jbc.M109.018010. 

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Self-made using Accelrys DS VisualizerGIMP and Inkscape

Date of upload

17-11-2014

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Author

Brenton

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To HM Wiki: Fuse809.

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Date/TimeThumbnailDimensionsUserComment
current07:24, November 17, 2014Thumbnail for version as of 07:24, November 17, 20143,979 × 1,807 (1.12 MB)Fuse809 (wall | contribs){{Information |Description=Structure of methotrexate. Based on {{PDB|3EIG}}, or: : {{cite journal|last1=Volpato|first1=JP|last2=Yachnin|first2=BJ|last3=Blanchet|first3=J|last4=Guerrero|first4=V|last5=Poulin|first5=L|last6=Fossati|first6=E|last7=Ber...

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