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Structure of methotrexate. Based on:

Volpato, JP; Yachnin, BJ; Blanchet, J; Guerrero, V; Poulin, L; Fossati, E; Berghuis, AM; Pelletier, JN (24 July 2009). "Multiple conformers in active site of human dihydrofolate reductase F31R/Q35E double mutant suggest structural basis for methotrexate resistance.". The Journal of Biological Chemistry 284 (30): 20079-89. doi:10.1074/jbc.M109.018010. PDB: 3EIG (RCSB PDB, PDBe). PMC 2740434PMID 19478082.


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current11:41, November 26, 2014Thumbnail for version as of 11:41, November 26, 20141,835 × 1,851 (354 KB)Fuse809 (wall | contribs){{Information |Description=Structure of methotrexate. Based on: : {{cite journal/PDB|last1=Volpato|first1=JP|last2=Yachnin|first2=BJ|last3=Blanchet|first3=J|last4=Guerrero|first4=V|last5=Poulin|first5=L|last6=Fossati|first6=E|last7=Berghuis|first7=...


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