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Cisplatin
Cisplatin2
2D structure of cisplatin
1KSB
3D structure of cisplatin (without its chloride ions) bound to DNA
Names
Synonyms CDDP, DDP, cis-DDP, NSC-119875, Peyrone's salt, sisplatin
Brand names Platamine, Platinex, Platinol, Platosin

IUPAC name
IUPAC name
Dichloroplatinumdiamine
Clinical information
Preg. cat.
AU: D
US: D
Legal status
AU: Prescription Only Medicine (S4)
CA: ℞-only
UK: POM
US: ℞-only
Routes Intravenous


Identifiers
ATC code L01XA01
ChemSpider 76401
DrugBank DB00515
PubChem 84691
MedlinePlus a684036
MeSH ID D002945
PDB IDs
PDBs
1KSB (RCSB, PDBe; NMR)
External links
DailyMed cisplatin search
Drugs.com international, monograph
Jmol 3D structure
Licensing data US FDA: link.
MSR monograph
emc cisplatin search
TGA-eBS cisplatin search
Chemical properties
Formula H6Cl2N2Pt
Mol. mass
Mol. mass for MFs
298.035 g/mol
SMILES
SMILES
N[Pt](N)(Cl)Cl
InChI
InChI
1S/2ClH.2H2N.Pt/h2*1H;2*1H2;/q;;2*-1;+4/p-2
InChIKey
InChIKey
DQLATGHUWYMOKM-UHFFFAOYSA-L


Cisplatin is a platinum compound that is used in the management of several cancers, including: anal, bladder, brain, cervical, endometrial, head and neck, lung, oesophageal, ovarian, stomach and testicular cancers and non-Hodgkin lymphomas, neuroblastoma and sarcoma of bone and soft tissue.[1]



External linksEdit

Reference listEdit

  1. Brayfield, A, ed. (13 December 2013). "Cisplatin". Martindale: The Complete Drug Reference. London, UK: Pharmaceutical Press. Retrieved 8 December 2014. 

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