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Chlorpromazine
Chlorpromazine
Synonyms Aminazine
Brand names Largactil, Thorazine
IUPAC name

IUPAC name
3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethyl-1-propanamine
ChemSpider

2625

DrugBank

DB00477

PubChem

2726

PDB fields

N/A

Formula

C17H19ClN2S

InChI
InChI
1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3
InChIKey
InChIKey
ZPEIMTDSQAKGNT-UHFFFAOYSA-N
SMILES
SMILES
CN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl
(Jmol 3D structure)
Mol. mass

318.8642 g/mol

Chlorpromazine is a typical antipsychotic, the first antipsychotic to be developed. It is very sedating, prone to cause weight gain, movement disorders, high blood sugar and other problems (including a small yet significant risk of causing liver problems). Its major medical uses include: bipolar mania, anxiety, schizophrenia, hypothermia (low body temperature), nausea and vomiting in palliative care, intractable hiccups, severely disturbed, agitated, or violent behaviour, tetanus and acute intermittent porphyria.[1]

External linksEdit

Reference listEdit

  1. Brayfield, A, ed. (12 May 2014). "Chlorpromazine". Martindale: The Complete Drug Reference. London, UK: Pharmaceutical Press. Retrieved 18 August 2014. 

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