Chimeric monoclonal antibodies are monoclonal antibodies that's Fab region is murine (mouse-derived) and their Fc region is human. All such agents that are used as drugs have the suffix, "-uximab" and include:
Several different techniques exist for chimeric monoclonal antibody production exist, including utilizing genetically-engineered Chinese Hamster Ovary (CHO) cell lines.
- NCBI Bookshelf provides free book resources on this topic.
- PubMed provides review articles from the past five years (limit to free review articles or to systematic reviews)
- The TRIP database provides clinical publications about evidence-based medicine.