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Carmustine
Carmustine
2D structure of carmustine
Carmustine
3D structure of carmustine
Names
Synonyms BCNU, NSC-409962, WR-139021
Brand names BiCNU, Gliadel

IUPAC name
IUPAC name
1,3-bis(2-chloroethyl)-1-nitrosourea
Clinical information
Preg. cat.
AU: D
US: D
Legal status
AU: Prescription Only Medicine (S4)
CA: ℞-only
UK: POM
US: ℞-only
Routes Intravenous, intralesional[note 1]


Identifiers
ATC code L01AD01
ChemSpider 2480
DrugBank DB00262
PubChem 2578
MedlinePlus a682060
MeSH ID D002330
External links
DailyMed carmustine search
Drugs.com international, monograph
Jmol 3D structure
Licensing data EU EMA: link.
US FDA: link.
MSR monograph
emc carmustine search
TGA-eBS carmustine search
Chemical properties
Formula C5H9Cl2N3O2
Mol. mass
Mol. mass for MFs
214.05 g/mol
SMILES
SMILES
ClCCNC(=O)N(CCCl)N=O
InChI
InChI
InChI=1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11)
InChIKey
InChIKey
DLGOEMSEDOSKAD-UHFFFAOYSA-N

Carmustine is a nitrosourea antineoplastic agent of the alkylating class.[1] It is primarily used to treat the following cancers: glioma, lymphoma and multiple myeloma.[1]

External linksEdit

NotesEdit

  1. By wafers that are surgically implanted into brain affected by glioma

Reference listEdit

  1. 1.0 1.1 Brayfield, A, ed. (13 December 2013). "Carmustine". Martindale: The Complete Drug Reference. London, UK: Pharmaceutical Press. Retrieved 26 January 2015. 

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