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Atomoxetine
Atomoxetine
Synonyms LY-135252, LY-139602, LY-139603, tomoxetine
Brand names Strattera
IUPAC name

IUPAC name
(3R)-N-methyl-3-(2-methylphenoxy)-3-phenylpropan-1-amine
ChemSpider

49516

DrugBank

DB00289

PubChem

54841

PDB fields

N/A

Formula

C17H21NO

InChI
InChI
1S/C17H21NO/c1-14-8-6-7-11-16(14)19-17(12-13-18-2)15-9-4-3-5-10-15/h3-11,17-18H,12-13H2,1-2H3/t17-/m1/s1
InChIKey
InChIKey
VHGCDTVCOLNTBX-QGZVFWFLSA-N
SMILES
SMILES
CC1=CC=CC=C1O[C@H](CCNC)C2=CC=CC=C2
(Jmol 3D structure)
Mol. mass

255.3547 g/mol

Atomoxetine is a substituted phenylpropylamine making it chemically related to fluoxetine, that serves as a selective noradrenaline reuptake inhibitor, with minimal (but not zero) affinity towards the serotonin transporter. It is primarily used in the treatment of attention-deficit/hyperactivity disorder (ADHD). In ADHD it is considered a first-line treatment, although the evidence suggests that it is less effective in this indication than stimulants.[1]

External linksEdit

Reference listEdit

  1. Royal Australasian College of Physicians (2009). "Australian Guidelines on Attention Deficit Hyperactivity Disorder (ADHD)" (PDF). National Health and Medical Research Council. Royal Australasian College of Physicians. Retrieved 17 September 2014. 

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