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Antiphospholipid syndrome
Synonyms
Synonyms
APS, lupus anticoagulant (LA) syndrome, Hughes' syndrome, sticky blood
MeSH D016736
ICD-9

289.81

ICD-10

D68.6

eMedicine

Overview
Presentation
DDx
Workup
Treatment
Medication}

Patient.co.uk

Professional Reference
Patient Reference

OMIM

107320

BHC

Antiphospholipid syndrome

Wikipedia

Antiphospholipid syndrome

Antiphospholipid Syndrome (APS) is a condition caused by antiphospholipid antibodies[note 1] which attack proteins associated with the phospholipids found within the plasma membranes of one's cells; they lead to an increased risk of blood clotting events (e.g., deep vein thrombosis, myocardial infarction, stroke and pulmonary embolism) and when they occur in pregnant women they can lead to serious pregnancy complications with fetal death being an unfortunately common complication.[1] Treatment is predominantly supportive (managing the complications as they arise) and aimed at preventing complications (e.g., many undergo anticoagulant therapy with heparin or warfarin), with few patients receiving treatment for the underlying autoimmune process.[1] It is also associated with systemic lupus erythematosus.[1]

External linksEdit

NotesEdit

  1. APA; they also occur in about 5% of healthy individuals

Reference listEdit

  1. 1.0 1.1 1.2 Movva, S; Belilos, E; Carsons, S (19 June 2014). Diamond, HS; Lozada, CJ; Talavera, F; Brent, LH; Mechaber, AJ, ed. "Antiphospholipid Syndrome". Medscape Reference. New York, USA: WebMD. Retrieved 12 November 2014. 

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